Ciupe, Stanca, Harel Dahari, and Alexander Ploss. (2024) 2024. “Mathematical Models of Early Hepatitis B Virus Dynamics in Humanized Mice.”. Bulletin of Mathematical Biology 86 (5): 53. doi:10.1007/s11538-024-01284-2.

Hartmann, Jordan, Marcella Cardoso, Maria Talarico, Devin Kenney, Madison Leone, Dagny Reese, Jacquelyn Turcinovic, et al. (2024) 2024. “Evasion of NKG2D-Mediated Cytotoxic Immunity by Sarbecoviruses”. Cell 187 (10): 2393-2410.e14. doi:10.1016/j.cell.2024.03.026.

Moreno, Jorge, Olga Dudchenko, Charles Feigin, Sarah Mereby, Zhuoxin Chen, Raul Ramos, Axel Almet, et al. (2024) 2024. “Emx2 Underlies the Development and Evolution of Marsupial Gliding Membranes.”. Nature 629 (8010): 127-35. doi:10.1038/s41586-024-07305-3.

Gomez-Moreno, Andoni, and Alexander Ploss. (2024) 2024. “Mechanisms of Hepatitis B Virus CccDNA and Minichromosome Formation and HBV Gene Transcription.”. Viruses 16 (4): 609. doi:10.3390/v16040609.

, Lena Allweiss, Chari Cohen, Joao Dias, Valeria Fumagalli, Haitao Guo, James Harris, et al. (2024) 2024. “Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B Virus.”. The Journal of General Virology 105 (5). doi:10.1099/jgv.0.001978.

Liu, Yongzhen, Stephanie Maya, Sebastian Carver, Aoife O’Connell, Anna Tseng, Hans Gertje, Kathleen Seneca, Ronald Nahass, Nicholas Crossland, and Alexander Ploss. (2024) 2024. “Development of a Dual Channel Detection System for Pan-Genotypic Simultaneous Quantification of Hepatitis B and Delta Viruses.”. Emerging Microbes & Infections 13 (1): 2350167. doi:10.1080/22221751.2024.2350167.

Wißing, Michael, Toni Meister, Maximilian Nocke, André Gömer, Mejrema Masovic, Leonard Knegendorf, Yannick Brüggemann, et al. (2024) 2024. “Genetic Determinants of Host- and Virus-Derived Insertions for Hepatitis E Virus Replication.”. Nature Communications 15 (1): 4855. doi:10.1038/s41467-024-49219-8.

Gomez-Moreno, Andoni, Jinchao Guo, Heidi Temple, and Alexander Ploss. (2024) 2024. “Formation and Transcriptional Regulation of Hepatitis B Virus Covalently Closed Circular DNA.”. Journal of Hepatology. doi:10.1016/j.jhep.2024.03.008.

Mesev, Emily, V, Emma G Guare, Alexander Ploss, and Jared E Toettcher. (2023) 2023. “Synthetic Heterodimers of Type III Interferon Receptors Require TYK2 for STAT Activation.”. Journal of Interferon & Cytokine Research : The Official Journal of the International Society for Interferon and Cytokine Research 43 (9): 414-26. doi:10.1089/jir.2023.0039.

Chen, Christopher, Benjamin Winer, Deborah Chavez, Bernadette Guerra, Kathleen Brasky, Stacey Eng, Eduardo Salas, et al. (2020) 2020. “Woolly Monkey-HBV Infection in Squirrel Monkeys As a Surrogate Nonhuman Primate Model of HBV Infection.”. Hepatology Communications 4 (3): 371-86. doi:10.1002/hep4.1471.

Nimgaonkar, Ila, Nicholas Archer, Isabelle Becher, Mohammad Shahrad, Robert LeDesma, André Mateus, Javier Caballero-Gómez, et al. (2021) 2021. “Isocotoin Suppresses Hepatitis E Virus Replication through Inhibition of Heat Shock Protein 90.”. Antiviral Research 185: 104997. doi:10.1016/j.antiviral.2020.104997.

Wei, Lei, and Alexander Ploss. (2022) 2022. “Rise above the Stress-Endoplasmic Reticulum Stress and Autophagy Enhance the Release of Hepatitis B Virus Subparticles.”. Hepatology (Baltimore, Md.) 75 (2): 248-51. doi:10.1002/hep.32273.

Tamura, Tomokazu, Jiayu Zhang, Vrinda Madan, Abhishek Biswas, Michael Schwoerer, Thomas Cafiero, Brigitte L Heller, Wei Wang, and Alexander Ploss. (2022) 2022. “Generation and Characterization of Genetically and Antigenically Diverse Infectious Clones of Dengue Virus Serotypes 1-4.”. Emerging Microbes & Infections 11 (1): 227-39. doi:10.1080/22221751.2021.2021808.

Wang, Ruixue, Saori Suzuki, Johnathan Guest, Brigitte Heller, Maricar Almeda, Alexander Andrianov, Alexander Marin, et al. (2022) 2022. “Induction of Broadly Neutralizing Antibodies Using a Secreted Form of the Hepatitis C Virus E1E2 Heterodimer As a Vaccine Candidate.”. Proceedings of the National Academy of Sciences of the United States of America 119 (11): e2112008119. doi:10.1073/pnas.2112008119.

Buksh, Benito, Steve Knutson, James Oakley V, Noah Bissonnette, Daniel Oblinsky, Michael Schwoerer, Ciaran Seath, et al. (2022) 2022. “μMap-Red: Proximity Labeling by Red Light Photocatalysis.”. Journal of the American Chemical Society 144 (14): 6154-62. doi:10.1021/jacs.2c01384.

Kenney, Devin, Aoife O’Connell, Jacquelyn Turcinovic, Paige Montanaro, Ryan Hekman, Tomokazu Tamura, Andrew Berneshawi, et al. (2022) 2022. “Humanized Mice Reveal a Macrophage-Enriched Gene Signature Defining Human Lung Tissue Protection During SARS-CoV-2 Infection.”. Cell Reports 39 (3): 110714. doi:10.1016/j.celrep.2022.110714.

Mesev, Emily, V, Aaron E Lin, Emma G Guare, Brigitte L Heller, Florian Douam, Britt Adamson, Jared E Toettcher, and Alexander Ploss. (2023) 2023. “Membrane-Proximal Motifs Encode Differences in Signaling Strength Between Type I and III Interferon Receptors.”. Science Signaling 16 (806): eadf5494. doi:10.1126/scisignal.adf5494.

Biswas, Sreya, Lauren Rust, Jochen Wettengel, Sofiya Yusova, Miranda Fischer, Julien Carson, Josie Johnson, et al. (2022) 2022. “Long-Term Hepatitis B Virus Infection of Rhesus Macaques Requires Suppression of Host Immunity.”. Nature Communications 13 (1): 2995. doi:10.1038/s41467-022-30593-0.

Liu, Yongzhen, Debby Park, Thomas Cafiero, Yaron Bram, Vasuretha Chandar, Anna Tseng, Hans Gertje, et al. (2022) 2022. “Molecular Clones of Genetically Distinct Hepatitis B Virus Genotypes Reveal Distinct Host and Drug Treatment Responses.”. JHEP Reports : Innovation in Hepatology 4 (9): 100535. doi:10.1016/j.jhepr.2022.100535.

Wei, Lei, Thomas Cafiero, Anna Tseng, Hans Gertje, Andrew Berneshawi, Nicholas Crossland, and Alexander Ploss. (2022) 2022. “Conversion of Hepatitis B Virus Relaxed Circular to Covalently Closed Circular DNA Is Supported in Murine Cells.”. JHEP Reports : Innovation in Hepatology 4 (9): 100534. doi:10.1016/j.jhepr.2022.100534.

Schwoerer, Michael, and Alexander Ploss. (2022) 2022. “Barriers to hepatitis C Virus Infection in Mice.”. Current Opinion in Virology 56: 101273. doi:10.1016/j.coviro.2022.101273.

Douam, Florian, and Alexander Ploss. (2022) 2022. “A Humanized ‘new-Trophil’ Mouse to Study Early Inflammatory Processes.”. Proceedings of the National Academy of Sciences of the United States of America 119 (49): e2216699119. doi:10.1073/pnas.2216699119.

Testoni, Barbara, and Alexander Ploss. (2023) 2023. “Cracking the Host Functional Network Involved in Hepatitis B Virus CccDNA Biology.”. Gut 72 (9): 1637-39. doi:10.1136/gutjnl-2022-329185.

LeDesma, Robert, Brigitte Heller, Abhishek Biswas, Stephanie Maya, Stefania Gili, John Higgins, and Alexander Ploss. (2023) 2023. “Structural Features Stabilized by Divalent Cation Coordination Within Hepatitis E Virus ORF1 Are Critical for Viral Replication.”. ELife 12. doi:10.7554/eLife.80529.

Liu, Yongzhen, Thomas Cafiero, Debby Park, Abhishek Biswas, Benjamin Winer, Cheul Cho, Yaron Bram, et al. (2023) 2023. “Targeted Viral Adaptation Generates a Simian-Tropic Hepatitis B Virus That Infects Marmoset Cells.”. Nature Communications 14 (1): 3582. doi:10.1038/s41467-023-39148-3.

Hogan, Glenn, Benjamin Winer, James Ahodantin, Julie Sellau, Tiffany Huang, Florian Douam, Masaya Funaki, Luis Chiriboga, Lishan Su, and Alexander Ploss. (2023) 2023. “Persistent Hepatitis B Virus and HIV Coinfections in Dually Humanized Mice Engrafted With Human Liver and Immune System.”. Journal of Medical Virology 95 (7): e28930. doi:10.1002/jmv.28930.

Johnson, Matthew, Sha Li, Christian Guerrero-Juarez, Pearson Miller, Benjamin Brack, Sarah Mereby, Jorge Moreno, et al. (2023) 2023. “A Multifunctional Wnt Regulator Underlies the Evolution of Rodent Stripe Patterns.”. Nature Ecology & Evolution 7 (12): 2143-59. doi:10.1038/s41559-023-02213-7.

Berggren, Keith, Robert Schwartz, Ralph Kleiner, and Alexander Ploss. (2024) 2024. “The Impact of Epitranscriptomic Modifications on Liver Disease.”. Trends in Endocrinology and Metabolism: TEM, 331-46. doi:10.1016/j.tem.2023.12.007.

Maya, Stephanie, Leeor Hershkovich, Fabian Cardozo-Ojeda, Elham Shirvani-Dastgerdi, Jay Srinivas, Louis Shekhtman, Susan Uprichard, et al. (2023) 2023. “Hepatitis Delta Virus RNA Decline Post-Inoculation in Human NTCP Transgenic Mice Is Biphasic.”. MBio 14 (4): e0100823. doi:10.1128/mbio.01008-23.

Douam, Florian, Carly G. K. Ziegler, Gabriela Hrebikova, Bruno Fant, Robert Leach, Lance Parsons, Wei Wang, et al. 2018. “Selective Expansion of Myeloid and NK Cells in Humanized Mice Yields Human-Like Vaccine Responses.”

Ploss, Alexander, An Tran, Ewa Menet, Ingrid Leiner, and Eric Pamer. (2005) 2005. “Cross-Recognition of N-Formylmethionine Peptides Is a General Characteristic of H2-M3-Restricted CD8+ T Cells.”. Infect Immun 73 (7): 4423-6. doi:10.1128/IAI.73.7.4423-4426.2005.

Dao, Tao, Donglin Guo, Alexander Ploss, Amy Stolzer, Carolyn Saylor, Tamar Boursalian, Jin Seon Im, and Derek Sant’Angelo. (2004) 2004. “Development of CD1d-Restricted NKT Cells in the Mouse Thymus.”. Eur J Immunol 34 (12): 3542-52. doi:10.1002/eji.200425546.

Wong, Phillip, María Lara-Tejero, Alexander Ploss, Ingrid Leiner, and Eric Pamer. (2004) 2004. “Rapid Development of T Cell Memory.”. J Immunol 172 (12): 7239-45.

Ploss, Alexander, Gregoire Lauvau, Brian Contos, Kristen Kerksiek, Patrick Guirnalda, Ingrid Leiner, Laurel Lenz, Michael Bevan, and Eric Pamer. (2003) 2003. “Promiscuity of MHC Class Ib-Restricted T Cell Responses.”. J Immunol 171 (11): 5948-55.

Kerksiek, Kristen, Alexander Ploss, Ingrid Leiner, Dirk Busch, and Eric Pamer. (2003) 2003. “H2-M3-Restricted Memory T Cells: Persistence and Activation Without Expansion.”. J Immunol 170 (4): 1862-9.

Lindenbach, Brett, Philip Meuleman, Alexander Ploss, Thomas Vanwolleghem, Andrew Syder, Jane McKeating, Robert Lanford, et al. (2006) 2006. “Cell Culture-Grown Hepatitis C Virus Is Infectious in Vivo and Can Be Recultured in Vitro.”. Proc Natl Acad Sci U S A 103 (10): 3805-9. doi:10.1073/pnas.0511218103.

Ploss, Alexander, Ingrid Leiner, and Eric Pamer. (2005) 2005. “Distinct Regulation of H2-M3-Restricted Memory T Cell Responses in Lymph Node and Spleen.”. J Immunol 175 (9): 5998-6005.

Ploss, Alexander, Salman Khetani, Christopher Jones, Andrew Syder, Kartik Trehan, Valeriya Gaysinskaya, Kathy Mu, Kimberly Ritola, Charles Rice, and Sangeeta Bhatia. (2010) 2010. “Persistent Hepatitis C Virus Infection in Microscale Primary Human Hepatocyte Cultures.”. Proc Natl Acad Sci U S A 107 (7): 3141-5. doi:10.1073/pnas.0915130107.

Jones, Christopher, Maria Teresa Catanese, Lok Man Law, Salman Khetani, Andrew Syder, Alexander Ploss, Thomas Oh, et al. (2010) 2010. “Real-Time Imaging of Hepatitis C Virus Infection Using a Fluorescent Cell-Based Reporter System.”. Nat Biotechnol 28 (2): 167-71. doi:10.1038/nbt.1604.

Akondy, Rama, Nathan Monson, Joseph Miller, Srilatha Edupuganti, Dirk Teuwen, Hong Wu, Farah Quyyumi, et al. (2009) 2009. “The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response.”. J Immunol 183 (12): 7919-30. doi:10.4049/jimmunol.0803903.

Ploss, Alexander, and Charles Rice. (2009) 2009. “Towards a Small Animal Model for Hepatitis C.”. EMBO Rep 10 (11): 1220-7. doi:10.1038/embor.2009.223.

Legrand, Nicolas, Alexander Ploss, Rudi Balling, Pablo Becker, Chiara Borsotti, Nicolas Brezillon, Jennifer Debarry, et al. (2009) 2009. “Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook.”. Cell Host Microbe 6 (1): 5-9. doi:10.1016/j.chom.2009.06.006.

Strowig, Till, Cagan Gurer, Alexander Ploss, Yi-Fang Liu, Frida Arrey, Junji Sashihara, Gloria Koo, et al. (2009) 2009. “Priming of Protective T Cell Responses Against Virus-Induced Tumors in Mice With Human Immune System Components.”. J Exp Med 206 (6): 1423-34. doi:10.1084/jem.20081720.

Ploss, Alexander, Matthew Evans, Valeriya Gaysinskaya, Maryline Panis, Hana You, Ype Jong, and Charles Rice. (2009) 2009. “Human Occludin Is a Hepatitis C Virus Entry Factor Required for Infection of Mouse Cells.”. Nature 457 (7231): 882-6. doi:10.1038/nature07684.

Biswas, Partha Sarathi, Virginia Pedicord, Alexander Ploss, Ewa Menet, Ingrid Leiner, and Eric Pamer. (2007) 2007. “Pathogen-Specific CD8 T Cell Responses Are Directly Inhibited by IL-10.”. J Immunol 179 (7): 4520-8.

Dorner, Marcus, Joshua Horwitz, Justin Robbins, Walter Barry, Qian Feng, Kathy Mu, Christopher Jones, et al. (2011) 2011. “A Genetically Humanized Mouse Model for Hepatitis C Virus Infection.”. Nature 474 (7350): 208-11. doi:10.1038/nature10168.

Billerbeck, Eva, Walter Barry, Kathy Mu, Marcus Dorner, Charles Rice, and Alexander Ploss. (2011) 2011. “Development of Human CD4+FoxP3+ Regulatory T Cells in Human Stem Cell Factor-, Granulocyte-Macrophage Colony-Stimulating Factor-, and Interleukin-3-Expressing NOD-SCID IL2Rγ(null) Humanized Mice.”. Blood 117 (11): 3076-86. doi:10.1182/blood-2010-08-301507.

Washburn, Michael, Moses Bility, Liguo Zhang, Grigoriy Kovalev, Adam Buntzman, Jeffery Frelinger, Walter Barry, Alexander Ploss, Charles Rice, and Lishan Su. (2011) 2011. “A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease.”. Gastroenterology 140 (4): 1334-44. doi:10.1053/j.gastro.2011.01.001.

Jong, Ype, Charles Rice, and Alexander Ploss. (2011) 2011. “Evaluation of Combination Therapy Against Hepatitis C Virus Infection in Human Liver Chimeric Mice.”. J Hepatol 54 (5): 848-50. doi:10.1016/j.jhep.2010.09.034.

Gerold, Gisa, Charles Rice, and Alexander Ploss. (2010) 2010. “Teaching New Tricks to an Old Foe: Murinizing Hepatitis C Virus.”. Hepatology 52 (6): 2233-6. doi:10.1002/hep.24045.