Nelson, Amy, Saloni Sinha, Sydney J Mullin, Sebastian S Carver, Thomas R Cafiero, Aaron E Lin, Robert E Schwartz, and Alexander Ploss. (2025) 2025. “STAT1-Mediated Interferon Signaling in the Hematopoietic System Is Essential for Restricting Usutu Virus Infection in Vivo”. PLOS Neglected Tropical Diseases 19 (7): e0013317. doi:10.1371/journal.pntd.0013317.

Zhang, Jiayu, Elizabeth C Chavez, Melina Winkler, Jianche Liu, Sebastian Carver, Aaron E Lin, Abhishek Biswas, et al. (2025) 2025. “Amino Acid Changes in Two Viral Proteins Drive Attenuation of the Yellow Fever 17D Vaccine”. Nature Microbiology 10 (8): 1902-17. doi:10.1038/s41564-025-02047-y.

Xiang, Jinhua, James H McLinden, Qing Chang, Micaela Fosdick, Hillel Haim, Alexander Ploss, Wesley Hottel, et al. (2025) 2025. “Characterization of Serotype-Specific Dengue Virus T Cell Inhibition”. The Journal of Infectious Diseases. doi:10.1093/infdis/jiaf241.

Kulakova, Liudmila, Kiki H Li, Austin W T Chiang, Michael P Schwoerer, Saori Suzuki, Sanne Schoffelen, Khadija H Elkholy, et al. (2025) 2025. “Glycoengineering of the Hepatitis C Virus E2 Glycoprotein Improves Biochemical Properties and Enhances Immunogenicity”. NPJ Vaccines 10 (1): 121. doi:10.1038/s41541-025-01161-6.

Brown, Richard, Birthe Tegtmeyer, Julie Sheldon, Tanvi Khera, , Daniel Todt, Gabrielle Vieyres, et al. (2020) 2020. “Liver-Expressed and Limit Hepatitis C Virus Cross-Species Transmission to Mice.”. Science Advances 6 (45). doi:10.1126/sciadv.abd3233.

Ramanathan, Harish, Shuo Zhang, Florian Douam, Katrina Mar, Jinhong Chang, Priscilla Yang, John Schoggins, Alexander Ploss, and Brett Lindenbach. (2020) 2020. “A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP P97) As an Essential Host Factor for Flavivirus Uncoating.”. MBio 11 (2). doi:10.1128/mBio.00467-20.

Winer, Benjamin, Kimberly Edgel, Xiaoyan Zou, Julie Sellau, Sri Hadiwidjojo, Lindsey Garver, Christin McDonough, et al. (2020) 2020. “Identification of Plasmodium Falciparum Proteoforms from Liver Stage Models.”. Malaria Journal 19 (1): 10. doi:10.1186/s12936-019-3093-3.

Akkina, Ramesh, Daniel Barber, Moses Bility, Karl-Dimiter Bissig, Benjamin Burwitz, Katrin Eichelberg, Janice Endsley, et al. (2020) 2020. “Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop.”. Current HIV Research 18 (1): 19-28. doi:10.2174/1570162X18666191223114019.

Ploss, Alexander, and Amit Kapoor. (2020) 2020. “Animal Models of Hepatitis C Virus Infection.”. Cold Spring Harbor Perspectives in Medicine 10 (5). doi:10.1101/cshperspect.a036970.

Maya, Stephanie, and Alexander Ploss. (2020) 2020. “Master of Disguise: Hepatitis Delta Virus Packaging and Spread Facilitated by Diverse Viral Envelope Proteins.”. Hepatology (Baltimore, Md.) 71 (1): 380-82. doi:10.1002/hep.30922.

Ploss, Alexander, Hélène Strick-Marchand, and Wenhui Li. (2021) 2021. “Animal Models for Hepatitis B: Does the Supply Meet the Demand?”. Gastroenterology 160 (5): 1437-42. doi:10.1053/j.gastro.2020.11.056.

Zakh, Rami, Alexander Churkin, William Bietsch, Menachem Lachiany, Scott Cotler, Alexander Ploss, Harel Dahari, and Danny Barash. (2021) 2021. “A Mathematical Model for Early HBV and -HDV Kinetics During Anti-HDV Treatment.”. Mathematics (Basel, Switzerland) 9 (24). doi:10.3390/math9243323.

Sanders, David, Chanelle Jumper, Paul Ackerman, Dan Bracha, Anita Donlic, Hahn Kim, Devin Kenney, et al. (2021) 2021. “SARS-CoV-2 Requires Cholesterol for Viral Entry and Pathological Syncytia Formation.”. ELife 10. doi:10.7554/eLife.65962.

Shekhtman, Louis, Scott Cotler, Alexander Ploss, and Harel Dahari. (2022) 2022. “Mathematical Modeling Suggests That Entry-Inhibitor Bulevirtide May Interfere With Hepatitis D Virus Clearance from Circulation.”. Journal of Hepatology 76 (5): 1229-31. doi:10.1016/j.jhep.2021.12.030.

Suzuki, Saori, Jacob Geri, Steve Knutson, Harris Bell-Temin, Tomokazu Tamura, David Fernández, Gabrielle Lovett, et al. (2022) 2022. “Photochemical Identification of Auxiliary Severe Acute Respiratory Syndrome Coronavirus 2 Host Entry Factors Using μMap.”. Journal of the American Chemical Society 144 (36): 16604-11. doi:10.1021/jacs.2c06806.

Nelson, Amy, and Alexander Ploss. (2024) 2024. “Emerging Mosquito-Borne Flaviviruses”. MBio 15 (12): e0294624. doi:10.1128/mbio.02946-24.

Lin, Aaron E, Emily Mesev V, Jared E Toettcher, and Alexander Ploss. (2024) 2024. “Engineered Chimeric Receptors for Dissecting Interferon Signaling”. Journal of Virology 98 (10): e0168023. doi:10.1128/jvi.01680-23.

Gomez-Moreno, Andoni, Jinchao Guo, Heidi Temple, and Alexander Ploss. (2024) 2024. “Formation and Transcriptional Regulation of Hepatitis B Virus Covalently Closed Circular DNA”. Journal of Hepatology 81 (2): 367-69. doi:10.1016/j.jhep.2024.03.008.

Ciupe, Stanca, Harel Dahari, and Alexander Ploss. (2024) 2024. “Mathematical Models of Early Hepatitis B Virus Dynamics in Humanized Mice”. Bulletin of Mathematical Biology 86 (5): 53. doi:10.1007/s11538-024-01284-2.

Hartmann, Jordan, Marcella Cardoso, Maria Talarico, Devin Kenney, Madison Leone, Dagny Reese, Jacquelyn Turcinovic, et al. (2024) 2024. “Evasion of NKG2D-Mediated Cytotoxic Immunity by Sarbecoviruses”. Cell 187 (10): 2393-2410.e14. doi:10.1016/j.cell.2024.03.026.

Moreno, Jorge, Olga Dudchenko, Charles Feigin, Sarah Mereby, Zhuoxin Chen, Raul Ramos, Axel Almet, et al. (2024) 2024. “Emx2 Underlies the Development and Evolution of Marsupial Gliding Membranes”. Nature 629 (8010): 127-35. doi:10.1038/s41586-024-07305-3.

Gomez-Moreno, Andoni, and Alexander Ploss. (2024) 2024. “Mechanisms of Hepatitis B Virus CccDNA and Minichromosome Formation and HBV Gene Transcription”. Viruses 16 (4): 609. doi:10.3390/v16040609.

, Lena Allweiss, Chari Cohen, Joao Dias, Valeria Fumagalli, Haitao Guo, James Harris, et al. (2024) 2024. “Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B Virus”. The Journal of General Virology 105 (5). doi:10.1099/jgv.0.001978.

Liu, Yongzhen, Stephanie Maya, Sebastian Carver, Aoife O’Connell, Anna Tseng, Hans Gertje, Kathleen Seneca, Ronald Nahass, Nicholas Crossland, and Alexander Ploss. (2024) 2024. “Development of a Dual Channel Detection System for Pan-Genotypic Simultaneous Quantification of Hepatitis B and Delta Viruses”. Emerging Microbes & Infections 13 (1): 2350167. doi:10.1080/22221751.2024.2350167.

Wißing, Michael, Toni Meister, Maximilian Nocke, André Gömer, Mejrema Masovic, Leonard Knegendorf, Yannick Brüggemann, et al. (2024) 2024. “Genetic Determinants of Host- and Virus-Derived Insertions for Hepatitis E Virus Replication”. Nature Communications 15 (1): 4855. doi:10.1038/s41467-024-49219-8.

Mesev, Emily, V, Emma G Guare, Alexander Ploss, and Jared E Toettcher. (2023) 2023. “Synthetic Heterodimers of Type III Interferon Receptors Require TYK2 for STAT Activation”. Journal of Interferon & Cytokine Research : The Official Journal of the International Society for Interferon and Cytokine Research 43 (9): 414-26. doi:10.1089/jir.2023.0039.

Chen, Christopher, Benjamin Winer, Deborah Chavez, Bernadette Guerra, Kathleen Brasky, Stacey Eng, Eduardo Salas, et al. (2020) 2020. “Woolly Monkey-HBV Infection in Squirrel Monkeys As a Surrogate Nonhuman Primate Model of HBV Infection.”. Hepatology Communications 4 (3): 371-86. doi:10.1002/hep4.1471.

Nimgaonkar, Ila, Nicholas Archer, Isabelle Becher, Mohammad Shahrad, Robert LeDesma, André Mateus, Javier Caballero-Gómez, et al. (2021) 2021. “Isocotoin Suppresses Hepatitis E Virus Replication through Inhibition of Heat Shock Protein 90.”. Antiviral Research 185: 104997. doi:10.1016/j.antiviral.2020.104997.

Wei, Lei, and Alexander Ploss. (2022) 2022. “Rise above the Stress-Endoplasmic Reticulum Stress and Autophagy Enhance the Release of Hepatitis B Virus Subparticles.”. Hepatology (Baltimore, Md.) 75 (2): 248-51. doi:10.1002/hep.32273.

Tamura, Tomokazu, Jiayu Zhang, Vrinda Madan, Abhishek Biswas, Michael Schwoerer, Thomas Cafiero, Brigitte L Heller, Wei Wang, and Alexander Ploss. (2022) 2022. “Generation and Characterization of Genetically and Antigenically Diverse Infectious Clones of Dengue Virus Serotypes 1-4.”. Emerging Microbes & Infections 11 (1): 227-39. doi:10.1080/22221751.2021.2021808.

Wang, Ruixue, Saori Suzuki, Johnathan Guest, Brigitte Heller, Maricar Almeda, Alexander Andrianov, Alexander Marin, et al. (2022) 2022. “Induction of Broadly Neutralizing Antibodies Using a Secreted Form of the Hepatitis C Virus E1E2 Heterodimer As a Vaccine Candidate.”. Proceedings of the National Academy of Sciences of the United States of America 119 (11): e2112008119. doi:10.1073/pnas.2112008119.

Buksh, Benito, Steve Knutson, James Oakley V, Noah Bissonnette, Daniel Oblinsky, Michael Schwoerer, Ciaran Seath, et al. (2022) 2022. “μMap-Red: Proximity Labeling by Red Light Photocatalysis.”. Journal of the American Chemical Society 144 (14): 6154-62. doi:10.1021/jacs.2c01384.

Kenney, Devin, Aoife O’Connell, Jacquelyn Turcinovic, Paige Montanaro, Ryan Hekman, Tomokazu Tamura, Andrew Berneshawi, et al. (2022) 2022. “Humanized Mice Reveal a Macrophage-Enriched Gene Signature Defining Human Lung Tissue Protection During SARS-CoV-2 Infection.”. Cell Reports 39 (3): 110714. doi:10.1016/j.celrep.2022.110714.

Mesev, Emily, V, Aaron E Lin, Emma G Guare, Brigitte L Heller, Florian Douam, Britt Adamson, Jared E Toettcher, and Alexander Ploss. (2023) 2023. “Membrane-Proximal Motifs Encode Differences in Signaling Strength Between Type I and III Interferon Receptors.”. Science Signaling 16 (806): eadf5494. doi:10.1126/scisignal.adf5494.

Biswas, Sreya, Lauren Rust, Jochen Wettengel, Sofiya Yusova, Miranda Fischer, Julien Carson, Josie Johnson, et al. (2022) 2022. “Long-Term Hepatitis B Virus Infection of Rhesus Macaques Requires Suppression of Host Immunity.”. Nature Communications 13 (1): 2995. doi:10.1038/s41467-022-30593-0.

Liu, Yongzhen, Debby Park, Thomas Cafiero, Yaron Bram, Vasuretha Chandar, Anna Tseng, Hans Gertje, et al. (2022) 2022. “Molecular Clones of Genetically Distinct Hepatitis B Virus Genotypes Reveal Distinct Host and Drug Treatment Responses.”. JHEP Reports : Innovation in Hepatology 4 (9): 100535. doi:10.1016/j.jhepr.2022.100535.

Wei, Lei, Thomas Cafiero, Anna Tseng, Hans Gertje, Andrew Berneshawi, Nicholas Crossland, and Alexander Ploss. (2022) 2022. “Conversion of Hepatitis B Virus Relaxed Circular to Covalently Closed Circular DNA Is Supported in Murine Cells.”. JHEP Reports : Innovation in Hepatology 4 (9): 100534. doi:10.1016/j.jhepr.2022.100534.

Schwoerer, Michael, and Alexander Ploss. (2022) 2022. “Barriers to Hepatitis C Virus Infection in Mice.”. Current Opinion in Virology 56: 101273. doi:10.1016/j.coviro.2022.101273.

Douam, Florian, and Alexander Ploss. (2022) 2022. “A Humanized ‘new-Trophil’ Mouse to Study Early Inflammatory Processes.”. Proceedings of the National Academy of Sciences of the United States of America 119 (49): e2216699119. doi:10.1073/pnas.2216699119.

Testoni, Barbara, and Alexander Ploss. (2023) 2023. “Cracking the Host Functional Network Involved in Hepatitis B Virus CccDNA Biology”. Gut 72 (9): 1637-39. doi:10.1136/gutjnl-2022-329185.

LeDesma, Robert, Brigitte Heller, Abhishek Biswas, Stephanie Maya, Stefania Gili, John Higgins, and Alexander Ploss. (2023) 2023. “Structural Features Stabilized by Divalent Cation Coordination Within Hepatitis E Virus ORF1 Are Critical for Viral Replication”. ELife 12. doi:10.7554/eLife.80529.

Liu, Yongzhen, Thomas Cafiero, Debby Park, Abhishek Biswas, Benjamin Winer, Cheul Cho, Yaron Bram, et al. (2023) 2023. “Targeted Viral Adaptation Generates a Simian-Tropic Hepatitis B Virus That Infects Marmoset Cells”. Nature Communications 14 (1): 3582. doi:10.1038/s41467-023-39148-3.

Hogan, Glenn, Benjamin Winer, James Ahodantin, Julie Sellau, Tiffany Huang, Florian Douam, Masaya Funaki, Luis Chiriboga, Lishan Su, and Alexander Ploss. (2023) 2023. “Persistent Hepatitis B Virus and HIV Coinfections in Dually Humanized Mice Engrafted With Human Liver and Immune System”. Journal of Medical Virology 95 (7): e28930. doi:10.1002/jmv.28930.

Johnson, Matthew, Sha Li, Christian Guerrero-Juarez, Pearson Miller, Benjamin Brack, Sarah Mereby, Jorge Moreno, et al. (2023) 2023. “A Multifunctional Wnt Regulator Underlies the Evolution of Rodent Stripe Patterns”. Nature Ecology & Evolution 7 (12): 2143-59. doi:10.1038/s41559-023-02213-7.

Berggren, Keith, Robert Schwartz, Ralph Kleiner, and Alexander Ploss. (2024) 2024. “The Impact of Epitranscriptomic Modifications on Liver Disease”. Trends in Endocrinology and Metabolism: TEM, 331-46. doi:10.1016/j.tem.2023.12.007.

Maya, Stephanie, Leeor Hershkovich, Fabian Cardozo-Ojeda, Elham Shirvani-Dastgerdi, Jay Srinivas, Louis Shekhtman, Susan Uprichard, et al. (2023) 2023. “Hepatitis Delta Virus RNA Decline Post-Inoculation in Human NTCP Transgenic Mice Is Biphasic”. MBio 14 (4): e0100823. doi:10.1128/mbio.01008-23.

Douam, Florian, Carly G. K. Ziegler, Gabriela Hrebikova, Bruno Fant, Robert Leach, Lance Parsons, Wei Wang, et al. 2018. “Selective Expansion of Myeloid and NK Cells in Humanized Mice Yields Human-Like Vaccine Responses.”

Wong, Phillip, María Lara-Tejero, Alexander Ploss, Ingrid Leiner, and Eric Pamer. (2004) 2004. “Rapid Development of T Cell Memory.”. J Immunol 172 (12): 7239-45.

Ploss, Alexander, Gregoire Lauvau, Brian Contos, Kristen Kerksiek, Patrick Guirnalda, Ingrid Leiner, Laurel Lenz, Michael Bevan, and Eric Pamer. (2003) 2003. “Promiscuity of MHC Class Ib-Restricted T Cell Responses.”. J Immunol 171 (11): 5948-55.

Kerksiek, Kristen, Alexander Ploss, Ingrid Leiner, Dirk Busch, and Eric Pamer. (2003) 2003. “H2-M3-Restricted Memory T Cells: Persistence and Activation Without Expansion.”. J Immunol 170 (4): 1862-9.